What is an mRNA vaccine?
The mRNA vaccine is a type of vaccine produced using the most advanced technology today.
Above In fact, scientists have been working on mRNA vaccines for decades. First of all, it is necessary to understand that mRNA, also known as messenger RNA, is a genetic material that contains coding information for the body to synthesize proteins. The mRNA vaccine will contain mRNA wrapped in a coating.
Several types of Covid-19 vaccines developed Developed using mRNA technology include: Pfizer-BioNTech vaccine Moderna vaccine Arcturus ARCT-154 vaccine.
MRNA vaccines have been previously researched for Zika fever rabies and cytomegalovirus (CMV).
Interest in these vaccines is growing because they can be developed in the laboratory using materials that are currently available meaning vaccine development will be faster than traditional vaccine-making methods.
How mRNA vaccines work
According to the CDC United States to activate the body’s immune response to help fight infectious diseases, the classic way of many previous vaccines is to inject a dose of inactivated or weakened virus or bacteria into the human body .
Covid-19 vaccines produced using mRNA technology will provide instructions to the human body’s cells to produce harmless “fragments” called “spike proteins” . This type of spike protein is found on the surface of the SARS-CoV-2 virus.
More specifically when mRNA vaccines are injected into the body the mRNAs will enter and locate inside immune cells stimulating the cells to produce protein fragments. After The protein fragments produced by the cell will break down the mRNAs and eliminate them.
Next the cells will display the protein fragments on the surface of the body’s immune system which will recognize that protein fragments that do not belong to the body and start to produce immune responses and produce antibodies against these protein fragments this is similar to what happens during infection SARS-CoV-2 naturally.
After a while the body learns to protect against future SARS-CoV-2 infection all other vaccines help the body fight off attacks from the virus that causes the disease Covid-19.
In addition, future mRNA vaccine technology may allow the creation of a vaccine that can protect against multiple diseases thus reducing the number of injections needed to protect the body can recover from common vaccine-preventable infections. In addition, scientists are currently researching using mRNA to activate the immune system to target specific cancer cells.
Some vaccine production technologies Other Covid-19
Inactivated Vaccines
The first way to make a vaccine is to take The disease-causing viruses themselves have been inactivated by using heat chemicals or radiation. This technology has been proven effective and this is how the influenza and polio vaccines with which it can be produced at a reasonable scale. However, requiring facilities to have special laboratories to safely grow viruses or bacteria requires a relatively long production time and may require 2 or 3 dose boosters.
Live attenuated vaccines
This technology takes the causing viruses that are alive but weakened Go. The measles, mumps and rubella (MMR) and chickenpox vaccines are good examples of this type of vaccine. The technological approach is similar to inactivated vaccines and can be produced at large scale. However, vaccines like these are not suitable for people with compromised immune systems.
Viral vector vaccines
Uses a safe virus to deliver specific components of the disease-causing virus (usually proteins) so that it can trigger the body’s immune response without causing disease. To do this requires inserting a few specific parts of the disease-causing virus inside a safe virus. The safe virus then acts as a vector to deliver the disease-causing virus proteins into the body. This protein will trigger an immune response. The Ebola vaccine is typical of a viral vector vaccine.
The vaccine uses part of the virus
Is these vaccines only use very specific parts (the subunits) of the virus that the immune system can recognize. This type of vaccine does not contain the entire virus or use a safe virus as a carrier (vector).
“
